Anti-undefined Antibody CANX,1541 Unconjugated BHA10208088

Mfr.No.	821-MSM1-P1ABX
Alternative Names	Calnexin ; CANX ; CNX ; IP90 ; Major histocompatibility complex class I antigen-binding protein p88 ; P90
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	5q35.3
Clonality	monoclonal
Description	It recognizes a protein of 90kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Host	Mouse
Immunogen	Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)
Isotype	IgG2b Kappa
Positive Control	HeLa, MCF-7 or U2OS cells. Kidney or small intestine.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P27824
Gene Id	821
Clone No	CANX, 1541
Symbol	CANX
Weight	90kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

ELISA, WB, IHC-F

Description

Order Ab without BSA, Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., ELISA ; WB ; IHC-F

Dilution