Anti-Melanoma Marker (MART-1 + gp100 + Tyrosinase) Antibody BHA10207210

Mfr.No.	MSM1-701-P1ABX
Alternative Names	Melanoma antigen recognized by T-cells 1 (MART-1) ; TYR ; PMEL17 ; MLAN-A
Categories	Primary Antibodies ; Tag & Cell Markers
Cellular Localization	Cytoplasmic
Clonality	monoclonal
Description	This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Host	Mouse
Immunogen	Recombinant hMART-1 protein (M2-7C10; M2-9E3); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Positive Control	SK-MEL-13 and SK-MEL-19 Melanoma cell lines; Melanomas
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q16655; P14679; P40967
Uniprot	154069; 503555; 95972
Gene Id	2315;7299;6490

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

IHC-F

Description

(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IHC-F

Dilution

IHC-F

0.5-1.0μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10207210	MSM1-701-P1ABX	100µg	$393.20		Add to Cart

Anti-Melanoma Marker (MART-1 + gp100 + Tyrosinase) Antibody BHA10207210

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