Anti-VEGI (Vascular Endothelial Growth Inhibitor) Antibody BHA10206982

Mfr.No.	9966-MSM1-P0
Alternative Names	TNF ligand-related molecule 1 (TL1A) ; Tumor necrosis factor (ligand) superfamily member 15 (TNFSF15) ; Vascular endothelial growth inhibitor 192a ; Vascular endothelial growth inhibitor (VEGI) ; VEGI192A
Categories	Primary Antibodies
Cellular Localization	Cell Surface(secreted)
Chromosome Location	9q32
Clonality	Monoclonal
Description	VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.
Host	Mouse
Immunogen	Recombinant human full-length VEGI fragment
Positive Control	Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	O95150
Uniprot	241382
Gene Id	9966

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) ,Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	1-2μg/ml for 60 minutes at RT
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206982	9966-MSM1-P0	20µg	$204.67		Add to Cart
BHA10206982	9966-MSM1-P0	100µg	$393.20		Add to Cart

Anti-VEGI (Vascular Endothelial Growth Inhibitor) Antibody BHA10206982

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