Anti-Plasma Cell Marker Antibody BHA10207146

Mfr.No.	MSM1-47-P0
Alternative Names	Plasma B cell ; Plasmocytes
Categories	Primary Antibodies ; Tag & Cell Markers
Cellular Localization	Cytoplasmic
Clonality	monoclonal
Description	It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues.
Host	Mouse
Immunogen	Pancreatic cancer-related mucin
Positive Control	Tonsil or lymph node
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Not Known
Uniprot	Not Known
Gene Id	Not Known

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IHC-F

Dilution

IHC-F

0.1-0.2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10207146	MSM1-47-P0	20µg	$204.67		Add to Cart
BHA10207146	MSM1-47-P0	100µg	$393.20		Add to Cart

Anti-Plasma Cell Marker Antibody BHA10207146

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