Anti-CD34 Antibody BHA10206563

Mfr.No.	947-MSM5-P1ABX
Alternative Names	Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q32.2
Clonality	Monoclonal
Description	This antibody recognizes a carbohydrate epitope on a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34 (VI international workshop on human differentiation antigens). Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, it is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. CD34 expression is also found in vascular endothelium. Additionally, proliferating endothelial cells overexpress this molecule than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi s sarcoma, but shows low specificity.
Host	Mouse
Immunogen	Recombinant full-length human HPCA1 protein
Positive Control	KG-1 cells, Tonsil, or Angiosarcoma
Reactivity	Human, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P28906
Uniprot	374990
Gene Id	947

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
WB	0.5-1μg/ml
IHC-F	2-4μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206563	947-MSM5-P1ABX	100µg	$393.20		Add to Cart

Anti-CD34 Antibody BHA10206563

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