Anti-CD44 / HCAM Std. Antibody BHA10206641

Mfr.No.	960-MSM1-P1ABX
Alternative Names	LHR ; BA-1 ; chondroitin sulfate proteoglycan 8 (CSPG8) ; Epican ; Extracellular Matrix Receptor III (ECM III) ; GP90 Lymphocyte Homing Adhesion Receptor ; HCAM ; HCELL ; hematopoietic cell E- and L-selectin ligand ; Heparan Sulfate Proteoglycan
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	11p13
Clonality	Monoclonal
Description	Recognizes a cell surface glycoprotein of 80-95kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. This MAb selectively interferes with lymphocyte binding to lymph node, mucosal and synovial endothelium. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
Host	Mouse
Immunogen	Stimulated human leukocytes
Positive Control	HeLa cells or paracortex in tonsil or lymph node.
Reactivity	Human, Baboon, Green Monkey
Recombinant	FALSE
Regulatory	RUO

Swissprot	P16070
Uniprot	502328
Gene Id	960

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, Func, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; Func ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
Func	Order Ab without BSA & Azide
WB	0.5-1μg/ml
IHC-F	0.25-0.5μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206641	960-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-CD44 / HCAM Std. Antibody BHA10206641

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