Anti-CD30 / TNFRSF8 Antibody BHA10206462

Mfr.No.	943-MSM1-P1ABX
Alternative Names	CD30L receptor ; Cytokine receptor CD30 ; Ki-1 antigen ; Lymphocyte activation antigen CD30 ; Tumor necrosis factor receptor superfamily member 8 (TNFRSF8)
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1p36.22
Clonality	Monoclonal
Description	Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkinā€™s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
Host	Mouse
Immunogen	Human CD30 recombinant protein
Positive Control	Hodgkin’s lymphoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P28908
Uniprot	1314
Gene Id	943

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206462	943-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-CD30 / TNFRSF8 Antibody BHA10206462

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