Anti-CD28 Antibody BHA10206423

Mfr.No.	940-MSM3-P1ABX
Alternative Names	T-cell-specific surface glycoprotein CD28 ; Tp44
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	2q33.2
Clonality	Monoclonal
Description	Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Host	Mouse
Immunogen	Recombinant human CD28 protein
Positive Control	Jurkat cells or human lymph nodes and tonsils.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P10747
Uniprot	591629
Gene Id	940

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206423	940-MSM3-P1ABX	100µg	$393.20		Add to Cart

Anti-CD28 Antibody BHA10206423

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