Anti-BCL10 Antibody BHA10206013

Mfr.No.	8915-MSM1-P1ABX
Alternative Names	B-cell CLL/lymphoma 10 ; B-cell leukemia/lymphoma 10 ; CARD-containing molecule enhancing NF-kappa-B ; CARD-like apoptotic protein ; caspase-recruiting domain-containing protein ; CED-3/ICH-1 prodomain homologous E10-like regulator ; Cellular homolog of vCARMEN ; Cellular-E10 (cE10) ; CIPER ; hCLAP
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Nuclear
Chromosome Location	1p22.3
Clonality	Monoclonal
Description	BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFĪŗB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Host	Mouse
Immunogen	Human BCL10 recombinant protein (epitope aa122-168)
Positive Control	HepG2 cells or Lymphoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	O95999
Uniprot	193516
Gene Id	8915

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206013	8915-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-BCL10 Antibody BHA10206013

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