Anti-CD1a / HTA1 Antibody BHA10206043

Mfr.No.	909-MSM3-P1ABX
Alternative Names	Cortical thymocyte antigen CD1A ; Epidermal dendritic cell marker CD1a antibody ; FCB6 ; HTA1 ; T cell surface antigen T6 / Leu 6 ; T-Cell Surface Glycoprotein CD1A
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q23.1
Clonality	Monoclonal
Description	At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. ĀWhen combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).Ā
Host	Mouse
Immunogen	Human thymus cells (O10); Recombinant human CD1a protein (C1A/711)
Positive Control	MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P06126
Uniprot	1309
Gene Id	909

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206043	909-MSM3-P1ABX	100µg	$393.20		Add to Cart

Anti-CD1a / HTA1 Antibody BHA10206043

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