Anti-Thyroglobulin Antibody BHA10205229

Mfr.No.	7038-MSM5-P1ABX
Alternative Names	AITD3 ; hTG ; TDH3 ; Tg ; Tgn
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic (Secreted)
Chromosome Location	8q24.22
Clonality	Monoclonal
Description	Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. ĀPrior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. ĀThe vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Host	Mouse
Immunogen	Human thyroid follicular cells
Isotype	IgG1 Kappa
Positive Control	Thyroid
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01266
Uniprot	654591
Gene Id	7038

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IHC-F

Dilution

FACS	0.5-1.0μg/million cells in 0.1ml
IHC-F	0.5-1.0μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205229	7038-MSM5-P1ABX	100µg	$393.20		Add to Cart

Anti-Thyroglobulin Antibody BHA10205229

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