Cellular retinol-binding protein I ; CRBP1 ; CRBP2 ; RBP1 ; RBP2 ; RBP4 ; RBPC ; Retinol binding protein 1 ; Retinol binding protein 1 cellular ; Retinol binding protein 2 cellular
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic
Chromosome Location
10q23.33
Clonality
monoclonal
Description
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein-1 (RBP1). This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein post-transnationally and results in defective delivery and supply to the epidermal cells.
Host
Mouse
Immunogen
Recombinant human retinol binding protein-1 (RBP1)
Isotype
IgG1 Kappa
Positive Control
Hepatic or ovarian carcinoma
Reactivity
Human, Monkey, Goat, Rabbit, Rat, Mouse
Recombinant
FALSE
Regulatory
RUO
Swissprot
P02753; P09455; P50120
Uniprot
529571
Gene Id
5947;5948;5950
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IF ; IHC-F
Dilution
IF
1-2μg/ml
IHC-F
1-2μg/ml for 30 minutes at RT
No Description Available.
Reviews of Anti-Retinol Binding Protein-1 (RBP1) Antibody BHA10204663