NR3C3 ; Nuclear receptor subfamily 3 group C member 3 ; PGR ; PR ; PRA ; PRB ; Progesterone receptor form A ; Progesterone receptor form B
Categories
Primary Antibodies
Cellular Localization
Nucleus
Chromosome Location
11q22.1
Clonality
monoclonal
Description
This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Host
Mouse
Immunogen
Recombinant human Progesterone Receptor protein
Isotype
IgG1 Kappa
Positive Control
T47-D Cells or Breast Cancers.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P06401
Uniprot
2905
Gene Id
5241
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., IHC-F
Dilution
IHC-F
0.5-1μg/ml for 30 min at RT
Reviews of Anti-Progesterone Receptor Antibody BHA10204081