Anti-c-Myc Oncoprotein Antibody BHA10203587

Mfr.No.	4609-MSM3-P1ABX
Alternative Names	Class E basic helix-loop-helix protein 39 (bHLHe39) ; MRTL ; Myc2 ; Niard ; Nird ; Proto-oncogene c-Myc ; RNCMYC ; Transcription factor p64 ; Transcriptional regulator Myc-A ; V-Myc avian myelocytomatosis viral oncogene homolog
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	8q24.21
Clonality	Monoclonal
Description	The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.
Host	Mouse
Immunogen	Recombinant human c-myc protein
Isotype	IgG1 Kappa
Positive Control	HL-60 cells or breast carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01106
Uniprot	202453
Gene Id	4609

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203587	4609-MSM3-P1ABX	100µg	$393.20		Add to Cart

Anti-c-Myc Oncoprotein Antibody BHA10203587

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