Anti-MUC5AC (Mucin 5AC / Gastric Mucin) Antibody BHA10203538

Mfr.No.	4586-MSM6-P1ABX
Alternative Names	Apomucin Major Airway Glycoprotein ; Mucin 5 subtype AC tracheobronchial ; Mucin 5 Subtypes A And C ; Mucin 5AC oligomeric mucus/gel forming ; Tracheobronchial Mucin (TBM)
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	11p15.5
Clonality	Monoclonal
Description	Mucin 5AC glycoprotein (MUC5AC) is a 641kDa glycoprotein belonging to the superfamily of mucins. Mucins are high molecular weight glycoproteins produced by epithelial cells and can be divided into two families; secretory mucins and membrane bound mucins. MUC5AC is a mucus-forming secreted mucin that is found in normal gastric and tracheo-bronchial mucosa, but absent from normal colon. MUC5AC expression is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Host	Mouse
Immunogen	Recombinant fragment covering tandem repeats of human MUC5 protein (exact sequence is proprietary)
Isotype	IgG1 Kappa
Positive Control	Stomach or gastric carcinoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P98088 (Human)
Uniprot	534332 (Human)
Gene Id	4586 (Human)

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203538	4586-MSM6-P1ABX	100µg	$393.20		Add to Cart

Anti-MUC5AC (Mucin 5AC / Gastric Mucin) Antibody BHA10203538

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