Anti-Galectin-1 / Human Placental Lactogen (hPL) Antibody BHA10203001

Mfr.No.	3956-MSM1-P1ABX
Alternative Names	14kDa laminin-binding protein ; Beta-galactoside-binding lectin L-14-I ; Gal-1 ; GAL1 ; Galaptin ; Galectin-1 ; HLBP14 ; HPL ; Lactose-binding lectin 1 ; Lect14
Categories	Primary Antibodies
Cellular Localization	Extracellular matrix
Chromosome Location	22q13.1
Clonality	Monoclonal
Description	Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
Host	Mouse
Immunogen	Recombinant human Galectin-1 protein fragment (aa12-108) (exact sequence is proprietary)
Isotype	IgG1 Lambda
Positive Control	HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P09382
Uniprot	445351
Gene Id	3956

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; WB ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203001	3956-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-Galectin-1 / Human Placental Lactogen (hPL) Antibody BHA10203001

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