Anti-Lambda Light Chain Antibody BHA10202290

Mfr.No.	3535-MSM3-P1ABX
Alternative Names	Bence Jones Protein ; BJP ; IGLC 1/2/3 ; Mcg Marker ; Paraprotein
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic (Secreted)
Chromosome Location	22q11.22
Clonality	Monoclonal
Description	This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Host	Mouse
Immunogen	Purified human IgG
Isotype	IgG2a Kappa
Positive Control	293T, Raji or hPBL cells. Tonsil or Spleen
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01701; P01842
Uniprot	449585
Gene Id	3535;3546

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-F	0.25-0.5μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202290	3535-MSM3-P1ABX	100µg	$393.20		Add to Cart

Anti-Lambda Light Chain Antibody BHA10202290

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