Anti-Kappa Light Chain Antibody BHA10202271

Mfr.No.	3514-MSM8-P1ABX
Alternative Names	HCAK1 ; Ig Kappa Chain C Region ; IGKC ; Immunoglobulin KM
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic (Secreted)
Chromosome Location	2p11.2
Clonality	Monoclonal
Description	This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Host	Mouse
Immunogen	Recombinant human full-length Ig kappa chain
Isotype	IgG1 Kappa
Positive Control	293T, Raji or hPBL cells. Tonsil or Spleen
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01601 ; P01834
Uniprot	449609
Gene Id	3514

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10202271	3514-MSM8-P1ABX	100µg	$393.20		Add to Cart

Anti-Kappa Light Chain Antibody BHA10202271

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