Anti-GP2 (Glycoprotein 2) / ZAP75 Antibody BHA10201639

Mfr.No.	2813-MSM2-P1ABX
Alternative Names	Glycoprotein 2 (zymogen granule membrane) ; GP2 ; Pancreatic zymogen granule membrane associated protein GP2 ; Pancreatic zymogen granule membrane protein GP-2 ; ZAP75
Categories	Primary Antibodies
Cellular Localization	Cell Surface(secreted)
Chromosome Location	16p12
Clonality	Monoclonal
Description	GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
Host	Mouse
Immunogen	Recombinant human GP2 protein fragment (aa35-179) (exact sequence is proprietary)
Isotype	IgG
Positive Control	PANC-1 cells. Pancreas
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P55259
Uniprot	53985
Gene Id	2813

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10201639	2813-MSM2-P1ABX	100µg	$393.20		Add to Cart

Anti-GP2 (Glycoprotein 2) / ZAP75 Antibody BHA10201639

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