A transferase ; ABO ; B transferase ; CD173 ; Fucosylglycoprotein 3-alpha-galactosyltransferase ; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase ; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase ; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase ; Histo-blood group A transferase ; Histo-blood group B transferase
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
9q34.2
Clonality
monoclonal
Description
This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Host
Mouse
Immunogen
Mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A
Isotype
IgM Kappa
Positive Control
KG1 cells or human colorectal carcinoma tissues.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P16442
Uniprot
654423
Gene Id
28
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
AGG, IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., AGG ; IF ; IHC-F
Dilution
AGG
IF
0.5-1μg/ml
IHC-F
0.5-1.0μg/ml for 30 minutes at RT
Reviews of Anti-Blood Group Antigen A (CD173) Antibody BHA10201608