Anti-MALT1 Antibody BHA10200364

Mfr.No.	10892-MSM1-P1ABX
Alternative Names	Caspase-like protein ; MALT lymphoma-associated translocation ; MLT1 ; Mucosa-associated lymphoid tissue lymphoma translocation protein 1 ; Paracaspase
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	18q21.32
Clonality	Monoclonal
Description	Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.
Host	Mouse
Immunogen	Human MALT1 recombinant fragment (aa701-808)
Isotype	IgG1 Kappa
Positive Control	Jurkat, Daudi or HeLa cells. Tonsil or lymphoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9UDY8
Uniprot	601217
Gene Id	10892

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200364	10892-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-MALT1 Antibody BHA10200364

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