Anti-PDGFRB Antibody BHA11308911

Mfr.No.	BS9886M
Alternative Names	Platelet-derived growth factor receptor beta ; PDGF-R-beta ; PDGFR-beta ; Beta platelet-derived growth factor receptor ; Beta-type platelet-derived growth factor receptor ; CD140 antigen-like family member B ; Platelet-derived growth factor receptor 1 ; PDGFR-1 ; CD140b ; PDGFRB ; PDGFR ; PDGFR1 ; PDGFRβ
Antigen	PDGFRB
Categories	Primary Antibodies
Chromosome Location	5q32
Clonality	monoclonal
Description	Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.
Host	Rabbit
Immunogen	Recombinant antibody.
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Description	Product: Recombinant Rabbit Monoclonal Antibody. 1TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. Specificity:* This antibody detects endogenous levels of PDGFR-β and does not cross-react with related proteins.
Purity	Protein A affinity purified
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.