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Home / Primary Antibodies / IHC Antibodies

Anti-CYP4F2 Antibody BHA11308764

SKU : BHA11308764

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Mfr.No.	BS9135
Alternative Names	Cyp4f14 ; CYPIVF1 ; Cytochrome P450 LTB omega ; Cytochrome P450 ; family 4 ; subfamily F ; polypeptide 2 ; EC 1.14.14.1 ; Leukotriene B(4) 20 monooxygenase ; Leukotriene B(4) omega hydroxylase ; MGC126966 ; MGC93476 ; P450 A3
Categories	Primary Antibodies
Chromosome Location	19p13.12
Clonality	polyclonal
Description	CYP4F isoforms are involved in the oxidation of important cellular mediators, such as leukotriene B4 (LTB4) and prostaglandins. CYP4F2 catalyzes ω-hydroxylation of LTB4 to a less potent proinflammatory eicosanoid, 20-OH-LTB4, as well as arachidonic acid. CYP4F2 is expressed in liver and kidney. Its expression is repressed by peroxisomal proliferators and induced by retinoic acid. X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder biochemically characterized by elevated levels of very long-chain fatty acids (VLCFA). CYP4F2 participates in the ω-hydroxylation of VLCFAs, which may provide an alternative mode of treatment for X-ALD patients.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 36-90 of Human CYP4F2.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P78329
Uniprot	P78329
Weight	60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CYP4F2 (M66) polyclonal antibody detects endogenous levels of CYP4F2 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11308764	BS9135	50µl	$190.44		Add to Cart
BHA11308764	BS9135	100µl	$294.44		Add to Cart

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