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Home / Primary Antibodies / IHC Antibodies

Anti-AKT2 Antibody BHA11302043

SKU : BHA11302043

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Mfr.No.	BS3584
Alternative Names	RAC-beta serine/threonine-protein kinase ; Protein kinase Akt-2 ; Protein kinase B beta ; PKB beta ; RAC-PK-beta ; AKT2 ; PKBβ
Categories	Primary Antibodies
Clonality	polyclonal
Description	AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH) domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 450-500 of Human AKT2.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P31751
Uniprot	P31751
Weight	60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: AKT2 (T468) polyclonal antibody detects endogenous levels of total AKT2 protein. This antibody does not cross-react with AKT1 or AKT3.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302043	BS3584	50µl	$190.44		Add to Cart
BHA11302043	BS3584	100µl	$294.44		Add to Cart

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