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Home / Primary Antibodies / IHC Antibodies

Anti-MARK4/MARK3/MARK2/MARK1 Antibody BHA11301715

SKU : BHA11301715

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Mfr.No.	BS3001
Alternative Names	Serine/threonine-protein kinase MARK1 ; MAP/microtubule affinity-regulating kinase 1 ; PAR1 homolog c ; Par-1c ; Par1c ; MARK1 ; KIAA1477 ; MARK ; Serine/threonine-protein kinase MARK2 ; ELKL motif kinase 1 ; EMK-1 ; MAP/microtubule affinity-regulating kinase 2 ; PAR1 homolog ; PAR1 homolog b ; Par-1b ; Par1b ; MARK2 ; EMK1 ; MAP/microtubule affinity-regulating kinase 3 ; C-TAK1 ; cTAK1 ; Cdc25C-associated protein kinase 1 ; ELKL motif kinase 2 ; EMK-2 ; Protein kinase STK10 ; Ser/Thr protein kinase PAR-1 ; Par-1a ; Serine/threonine-protein kinase p78 ; MARK3 ; CTAK1 ; EMK2 ; MAP/microtubule affinity-regulating kinase 4 ; MAP/microtubule affinity-regulating kinase-like 1 ; MARK4 ; KIAA1860 ; MARKL1
Antigen	MARK4/MARK3/MARK2/MARK1
Categories	Primary Antibodies
Clonality	polyclonal
Description	MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 180-230 of Human MARK1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9P0L2/Q7KZI7/P27448/Q96L34
Uniprot	Q9P0L2/Q7KZI7/P27448/Q96L34
Weight	80 to 92 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: MARK1/2/3/4 (N211) polyclonal antibody detects endogenous levels of total MARK protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301715	BS3001	50µl	$190.44		Add to Cart
BHA11301715	BS3001	100µl	$294.44		Add to Cart

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