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Home / Primary Antibodies / IHC Antibodies

Anti-CPN1 Antibody BHA11301644

SKU : BHA11301644

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Mfr.No.	BS2872
Alternative Names	Carboxypeptidase N catalytic chain ; CPN ; Anaphylatoxin inactivator ; Arginine carboxypeptidase ; Carboxypeptidase N polypeptide 1 ; Carboxypeptidase N small subunit Kininase-1 ; Lysine carboxypeptidase ; Plasma carboxypeptidase B ; Serum carboxypeptidase N ; SCPN ; ACBP ; CPN cat ; CPN-cat ; CPNcat
Categories	Primary Antibodies
Chromosome Location	10q24.2
Clonality	polyclonal
Description	Carboxypeptidase N (arginine carboxypeptidase or CPN) cleaves basic amino acid residues from the carboxy terminal of peptides and proteins. The enzyme plays a central role in regulating the biologic activity of peptides such as kinins and anaphylatoxins, and therefore is also known as kininase-1 and anaphylatoxin inactivator. CPN is a tetrameric complex consisting of two identical regulatory subunits (CPN reg) and two identical catalytic subunits (CPN cat). The two glycosylated CPN reg subunits protect the two CPN cat subunits and keep them in the circulation. CPN reg is a member of the leucinerich repeat family of proteins and the gene which encodes CPN reg maps to human chromosome 8p22-p23. CPN cat is a member of the regulatory B-type carboxypeptidase group and the gene which encodes CPN cat maps to human chromosome 10.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to the N-terminus of Human CPN1.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P15169
Uniprot	P15169
Weight	52 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: CPN1 (M25) polyclonal antibody detects endogenous levels of Carboxypeptidase N catalytic chain protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301644	BS2872	50µl	$190.44		Add to Cart
BHA11301644	BS2872	100µl	$294.44		Add to Cart

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