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Home / Primary Antibodies / IHC Antibodies

Anti-PRKAR1B Antibody BHA11301265

SKU : BHA11301265

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Mfr.No.	BS2269
Alternative Names	cAMP-dependent protein kinase type I-beta regulatory subunit ; PRKAR1B
Categories	Primary Antibodies
Chromosome Location	7p22.3
Clonality	polyclonal
Description	The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified, designated Cα, Cβ and Cγ, that each represent specific gene products. Cα and Cβ are closely related (93% amino acid sequence similarity), whereas Cγ displays 83% and 79% similarity to Cα and Cβ, respectively.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 120-160 of Human PKA Iβ reg.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P31321
Uniprot	P31321
Weight	43 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: PKA Iβ reg (F138) polyclonal antibody detects endogenous levels of PKA Iβ reg protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301265	BS2269	50µl	$190.44		Add to Cart
BHA11301265	BS2269	100µl	$294.44		Add to Cart

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