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Home / Primary Antibodies / IHC Antibodies

Anti-LPAR3 Antibody BHA11301548

SKU : BHA11301548

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Mfr.No.	BS2698
Alternative Names	Lysophosphatidic acid receptor 3 ; LPA receptor 3 ; LPA-3 ; Lysophosphatidic acid receptor Edg-7 ; LPAR3 ; EDG7 ; LPA3
Categories	Primary Antibodies
Chromosome Location	1p22.3
Clonality	polyclonal
Description	The EDG (endothelial differentiation gene) family of G protein-coupled receptors consists of eight family members that bind lysophospholipid (LPL) mediators, including sphingosine-1-phosphate (SPP) and lysophosphatidic acid (LPA). EDG-1, EDG-3, EDG-5 (also designated H218 and AGR16) and EDG-8 bind SPP with high affinity. EDG-6 is a low affinity receptor for SPP. LPA preferentially binds to EDG-2, EDG-4 and EDG-7. The EDG receptors couple to multiple G proteins to signal through Ras, MAP kinase, Rho, Phospholipase C or other tyrosine kinases, which lead to cell survival, growth, migration and differentiation. EDG-1 signals through Gi proteins to activate Akt and is expressed in glioma cells. EDG-2 is expressed in brain, especially in white matter tract regions, while EDG-3 is expressed in cardiovascular tissue and in cerebellum. EDG-4 is highly expressed on leukocytes and brain, and EDG-5 has wide tissue distribution, including cardiovascular tissue and brain.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 114-160 of Human EDG-7.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9UBY5
Uniprot	Q9UBY5
Weight	40 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: EDG-7 (L148) polyclonal antibody detects endogenous levels of EDG-7 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301548	BS2698	50µl	$190.44		Add to Cart
BHA11301548	BS2698	100µl	$294.44		Add to Cart

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