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Home / Primary Antibodies / IHC Antibodies

Anti-TNFSF13 Antibody BHA11300990

SKU : BHA11300990

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Mfr.No.	BS1893
Alternative Names	Tumor necrosis factor ligand superfamily member 13 ; A proliferation-inducing ligand ; APRIL ; TNF- and APOL-related leukocyte expressed ligand 2 ; TALL-2 ; TNF-related death ligand 1 ; TRDL-1 ; TRDL1 ; CD256 ; TNFSF13 ; APRIL ; TALL2 ; ZTNF2 ; ORF Names: UNQ383/PRO715
Antigen	TNFSF13
Categories	Primary Antibodies
Chromosome Location	17p13.1
Clonality	polyclonal
Description	A proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. APRIL is expressed in high levels in transformed cell lines and in human colon, thyroid, and lymphoid tumor tissues. APRIL is critically involved in the regulation of infections, inflammation, autoimmune diseases, and tissue homeostasis. APRIL is implicated in the regulation of tumor cell growth. The C-terminal extracellular domain has b jelly roll topography and is important in ligand trimerization. The binding of the ligand to its respective receptor induces oligomerization, initiating downstream signaling events. Intrinsic to oligomerization is the formation of the receptor binding site at the junction between neighboring subunits, creating a multivalent ligand.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 151-200 of Human APRIL.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	O75888
Uniprot	O75888
Weight	22 to 32 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: APRIL (S183) polyclonal antibody detects endogenous levels of APRIL protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300990	BS1893	50µl	$190.44		Add to Cart
BHA11300990	BS1893	100µl	$294.44		Add to Cart

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