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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hHLA-DPB1*04: 01
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-H2-
- Strain : Sperm cryoprese
- KI/KO Gene : H2-Ab1
- Synonyms : IAb; Ia2; Ia-2;
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hHLA-DPA1*03: 01
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-H2-
- Strain : Repository Live
- KI/KO Gene : H2-Aa
- Synonyms : Ia1; H2Aa; Ia-1
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hIL17A/hIL17F
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Il1
- Strain : Embryo cryopres
- KI/KO Gene : IL17A
- Synonyms : Il17; Ctla8; IL
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hCCR8(2)/hTIGIT
- Description : hTIGIT(NM-HU-20
- Nomenclature : C57BL/6Smoc-Tig
- Strain : Repository Live
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hCD27(2)/hFCGR2B
- Description : hCD27(2) (NM-HU
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : Fcgr2b
- Synonyms : AI528646; CD32
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hCD24/hSIGLEC10
- Description : hCD24(NM-HU-200
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Siglecg
- Synonyms : Siglec-G; Sigl
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hCD3E/hPD-L1
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Embryo cryopres
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD3E/hCD38(2)
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Embryo cryopres
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD3EDG/hCD28
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- KI/KO Gene : CD28
- Synonyms : CD3; T3e; AI5
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hCD3EDG/hCD47
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCEACAM5-Tg
- Description : These transgeni
- Nomenclature : C57BL/6Smoc-Tg(
- Strain : Sperm cryoprese
- KI/KO Gene : Cd52
- Synonyms : CEA,CD66e
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hCsf1/hCsf1r(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cs
- Strain : Repository Live
- KI/KO Gene : CSF1
- Synonyms : colony-stimulat
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hCSF1/hCSF1R(2)
- Description : hCSF1(NM-HU-190
- Nomenclature : C57BL/6Smoc-Csf
- Strain : Embryo cryopres
- KI/KO Gene : CSF1
- Synonyms : colony-stimulat
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hCTLA-4/hTIGIT
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hCTLA-4/hCCR8(BALB/c)
- Description : hCTLA4(BALB/c)(
- Nomenclature : BALB/cAnSmoc-Cc
- Strain : Repository Live
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hCTLA-4/4-1BB
- Description : This CTLA4 and
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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h4-1BB(2)/hPD-1
- Description : h4-1BB(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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h4-1BB(2)/hCD3E(2)
- Description : h4-1BB(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hB2M-HLA A2.1(NMG,2)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidIl
- Strain : Repository Live
- KI/KO Gene : B2m
- Synonyms : Ly-m11,beta2m,b
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hC5AR1/C5AR2
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-C5a
- Strain : Sperm cryoprese
- KI/KO Gene : C5AR1
- Synonyms : C5aR; C5r1; C
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