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Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hIL6/hIL6R(M-NSG)

    hIL6/hIL6R(M-NSG)

    • Description : Model Descripti
    • Nomenclature : M-NSG-Il6tm(hIL
    • Strain : Repository Live
  • hKLRG1

    hKLRG1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kl
    • Strain : Repository Live
    • KI/KO Gene : Klrg1
    • Synonyms : MAFA, 2F1-Ag, M
  • hLRRC15

    hLRRC15

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Strain : Developing
    • KI/KO Gene : Lrrc15
    • Synonyms : LIB, 5430427N11
  • hMADCAM1

    hMADCAM1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Strain : Developing
    • KI/KO Gene : Madcam1
    • Synonyms : AV211525, MAdCA
  • hMSTN

    hMSTN

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ms
    • Strain : Developing
    • KI/KO Gene : Mstn
    • Synonyms : Cmpt, Gdf8
  • hNCR3LG1-Tg

    hNCR3LG1-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Tgtn( hNCR3LG1)
  • hMUC1

    hMUC1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Muc1
  • hTP53(2)

    hTP53(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Trp53
  • hTNFSF14

    hTNFSF14

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Repository Live
    • Target : Cytokines
    • KI/KO Gene : Tnfsf14
  • hTTR

    hTTR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tt
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : Ttr
  • Itgam-IRES-hCD89/hIGHA1

    Itgam-IRES-hCD89/hIGHA1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-It
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Itgam
  • R26-LSL-hIL2 SP-hIL15(M-NSG)

    • Description : Model Descripti
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Gt(ROSA)26Sor
  • hIL5/hIL5R

    hIL5/hIL5R

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Embryo cryopres
    • Target : Other Targets
    • KI/KO Gene : IL5
  • hITGA5

    hITGA5

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-It
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Itga5
  • hITGA4

    hITGA4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-It
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Itga4
  • hINSR

    hINSR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-In
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Insr
  • hIL7(M-NSG)

    hIL7(M-NSG)

    • Description : Model Descripti
    • Nomenclature : M-NSG-Il7tm(hIL
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Il7
  • hKDR(BALB/c)

    hKDR(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Kd
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Kdr
  • hLEPR

    hLEPR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Le
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Lepr
  • hMASP1

    hMASP1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Masp1
  • hLRRC32

    hLRRC32

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Lrrc32
  • hMUC16

    hMUC16

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Muc16
  • hMUC1-c.462insC

    hMUC1-c.462insC

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Muc1
  • hNTRK2

    hNTRK2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nt
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Ntrk2
  • hNTRK1

    hNTRK1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nt
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Ntrk1