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Humanized Knockins

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Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

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  • hCDH3

    hCDH3

    hCDH3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • KI/KO Gene : Cdh3
    • Synonyms : Cadp, Cdhp, Pca
  • hCDH17

    hCDH17

    hCDH17

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • KI/KO Gene : Cdh17
    • Synonyms : HPT-1, HPT-1/LI
  • hENTPD1(3)

    hENTPD1(3)

    hENTPD1(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-En
    • Strain : Embryo cryopres
    • KI/KO Gene : Entpd1
    • Synonyms : Cd39, AA408691,
  • hENG

    hENG

    hENG

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-En
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Eng
  • hEDNRA

    hEDNRA

    hEDNRA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ed
    • Strain : Repository Live
    • Target : Tumor Targets
    • KI/KO Gene : Ednra
  • hF10

    hF10

    hF10

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F1
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : F10
  • hFCER1A

    hFCER1A

    hFCER1A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fc
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Fcer1a
  • hGABPB1L

    hGABPB1L

    hGABPB1L

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Gabpb1
  • hFGFR1

    hFGFR1

    hFGFR1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Fgfr1
  • hCD200R1

    hCD200R1

    hCD200R1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd200r1
  • hCD36(2)

    hCD36(2)

    hCD36(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd36
  • hCD4(2)

    hCD4(2)

    hCD4(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd4
  • hCD40/hCD40LG(BALB/c)

    hCD40/hCD40LG(BALB/c)

    hCD40/hCD40LG(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : CD40
  • hCD7(2)

    hCD7(2)

    hCD7(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd7
  • hCD7

    hCD7

    hCD7

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Repository Live
    • Target : Tumor Targets
    • KI/KO Gene : Cd7
  • hCD47/hSIRPA(2)/hCD38(2)

    hCD47/hSIRPA(2)/hCD38(2)

    hCD47/hSIRPA(2)/hCD38(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Si
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : SIRPA
  • hCEBPA

    hCEBPA

    hCEBPA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ce
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cebpa
  • hCEACAM6-Tg

    hCEACAM6-Tg

    hCEACAM6-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Tgtn(hCEACAM6)1
  • hADORA2A(BALB/c)

    hADORA2A(BALB/c)

    hADORA2A(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Ad
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Adora2a
  • hADAM17

    hADAM17

    hADAM17

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ad
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Adam17
  • hAPOB(1)

    hAPOB(1)

    hAPOB(1)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Apob
  • hAPOE3

    hAPOE3

    hAPOE3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : Apoe
  • hCALCA

    hCALCA

    hCALCA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ca
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : Calca
  • hIFNG

    hIFNG

    hIFNG

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-If
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : Ifng
  • hIL2RA/hTNFRSF1B

    hIL2RA/hTNFRSF1B

    hIL2RA/hTNFRSF1B

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : TNFRSF1B
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