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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-1/hCTLA-4(BALB/c)
- Description : hPD-1(NM-HU-190
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hPD-1/hCD27(2)
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : CD27
- Synonyms : Cd27; S152; T
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hPD-1/hPD-L1/hCD73(2)
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hIL17RA(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- KI/KO Gene : IL17RA
- Synonyms : Il17r; Cdw217
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hGPRC5D(2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Gp
- Strain : Developing
- KI/KO Gene : Gprc5d
- Synonyms : Il17r; Cdw217
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hIL12RB1(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- KI/KO Gene : Il12rb1
- Synonyms : CD212, IL-12R(b
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hIL1RL1/hIL4/hIL4R
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- KI/KO Gene : IL4Ra
- Synonyms : Il4r, CD124
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hIL4/hIL4R/hTSLP
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- KI/KO Gene : TSLP
- Synonyms : IL-22, Iltif, I
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hCSF2RB/hIL3/hCSF2
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cs
- Strain : Developing
- KI/KO Gene : IL3
- Synonyms : BPA, PSF, HCG
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hCD22(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : Cd22
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hCD3EDG/hB7H3
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD276
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hCD47(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Cd47
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hCEACAM1(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ce
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Ceacam1
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hPD-1/hSIGLEC15
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hPD-1/hPD-L1/hPD-L2
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hPD-L1(2)/hCCR8
- Description : hPD-1(2)(NM-HU-
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
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hPD-1/hVISTA
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Vis
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hPD-1/hTLR9
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hPD-L1/hSEMA4D
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
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hPD-L1/h4-1BB(2)
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
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hPD-L1(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
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hPD-L1/hTIGIT
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
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hTIGIT/hPVR
- Description : These mice are
- Nomenclature : C57BL/6Smoc-Tig
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : TIGIT
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