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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTIGIT/hPVR
- Nomenclature : C57BL/6JSmoc-Ti
- KI/KO Gene : TIGIT
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Immune Checkpoi
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hTNFRSF1B(BALB/c)
- Nomenclature : BALB/cAnSmoc-Tn
- KI/KO Gene : Tnfrsf1b
- Strain : Developing
- Description : Model Descripti
- Synonyms : p75, TNFBR, Tnf
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hTNFRSF10C
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : Tnfrsf23
- Strain : Developing
- Description : Model Descripti
- Synonyms : SOB, mSOB, Tnfr
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hIL6/hIL6R(M-NSG)
- Nomenclature : M-NSG-Il6tm(hIL
- Strain : Repository Live
- Description : Model Descripti
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hNCR3LG1-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- KI/KO Gene : Tgtn( hNCR3LG1)
- Strain : Developing
- Target : Immune Checkpoi
- Description : Model Descripti
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Itgam-IRES-hCD89/hIGHA1
- Nomenclature : C57BL/6JSmoc-It
- KI/KO Gene : Itgam
- Strain : Repository Live
- Target : Other Targets
- Description : Model Descripti
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R26-LSL-hIL2 SP-hIL15(M-NSG)
- Nomenclature : NOD-PrkdcscidIl
- KI/KO Gene : Gt(ROSA)26Sor
- Strain : Developing
- Description : Model Descripti
- Synonyms : R26, ROSA26, AV
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hIL5/hIL5R
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : IL5
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Description : Model Descripti
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