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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPCSK9/hANGPTL3(4)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Pc
- Strain : Developing
- KI/KO Gene : Pcsk9
- Synonyms : AI415265, AI747
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hPD-1/hPVRIG
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Pd
- Strain : Developing
- KI/KO Gene : Pdcd1
- Synonyms : PD-1, Pdc1, Ly1
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hGPRC5D(2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Gp
- Strain : Developing
- KI/KO Gene : Gprc5d
- Synonyms : Pdgfr, CD140b,
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hIL12RB1(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- KI/KO Gene : Il12rb1
- Synonyms : CD212, IL-12R(b
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hIL1RL1/hIL4/hIL4R
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- KI/KO Gene : IL4Ra
- Synonyms : Il4r, CD124
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hIL4/hIL4R/hTSLP
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- KI/KO Gene : TSLP
- Synonyms : IL-22, Iltif, I
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hCSF2RB/hIL3/hCSF2
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cs
- Strain : Developing
- KI/KO Gene : IL3
- Synonyms : BPA, PSF, HCG
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hCD22(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : Cd22
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hCD3EDG/hB7H3
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD276
-
hCD47(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Cd47
-
hCEACAM1(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ce
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Ceacam1
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