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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD28/hCD38(2)
- Description : hCD38(NM-HU-190
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : CD28
- Synonyms : Ly7, RP1, Ly78,
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hCD40/hCD40L
- Description : hCD40(NM-HU-000
- Nomenclature : C57BL/6Smoc-CD4
- Strain : Embryo cryopres
- KI/KO Gene : CD40
- Synonyms : IGM; p50; Bp5
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hCD40/hPD-1/hPD-L1
- Description : hPD-1/hPD-L1(NM
- Nomenclature : C57BL/6Smoc-Cd4
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hCTLA-4(2)
- Description : Extracellular d
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hTNFRSF10B
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : Tnfrsf10b
- Synonyms : DR, KI, MK, TR,
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hTNFR2/hPD-1/hPD-L1
- Description : hTNFRSF1B(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hTNFR2/hFCGR2B
- Description : hTNFRSF1B (NM-H
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : Fcgr2b
- Synonyms : AI528646; CD32
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