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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTNFSF11/hSIGLEC15
- Description : hTNFSF11(NM-HU-
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : SIRPA
- Synonyms : Bit; P84; SIR
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Rag2/IL2rg-KO/hCD40
- Description : The Rag2 and Il
- Nomenclature : C57BL/6Smoc-Cd4
- Strain : Developing
- KI/KO Gene : CD40
- Synonyms : IGM; p50; Bp5
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hIL2/hIL2RB/hIL2RG
- Description : hIL2RG(NM-HU-20
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2
- Synonyms : Il-2
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hIL2/hIL2RA
- Description : hIL2(NM-HU-1900
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2
- Synonyms : Il-2,I, CD25, I
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hIL2RA/hIL2RB/hIL2RG
- Description : hIL2RA(NM-HU-19
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2RA
- Synonyms : CD25; Il2r; I
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hIL3/hCSF2/hSIRPA(2)/hCD47
- Description : hIL3(NM-HU-1900
- Nomenclature : C57BL/6Smoc-Il3
- Strain : Repository Live
- KI/KO Gene : IL3
- Synonyms : BPA; PSF; HCG
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hIL4/hIL4R
- Description : These mice are
- Nomenclature : C57BL/6Smoc-Il4
- Strain : Repository Live
- KI/KO Gene : IL4
- Synonyms : Il-4; BSF-1
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hIL7(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- KI/KO Gene : Il7r
- Synonyms : CD127; IL-7Ralp
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hLILRB2-hLILRB3-Tg
- Description : These transgeni
- Nomenclature : C57BL/6Smoc-Tg(
- Strain : Repository Live
- KI/KO Gene : LILRB2
- Synonyms : ILT4; LIR2; CD8
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hOX40/Cd8a-IRES-Luc-2A-EGFP
- Description : hOX40(NM-HU-000
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Synonyms : Ox40; ACT35;
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hPD-1(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Repository Live
- KI/KO Gene : Tnfrsf4
- Synonyms : PD-1 Pdc1 Ly101
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hPD-1/hPD-L1
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hLAG3/hTIGIT
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : LAG3
- Synonyms : Ly66; CD223;
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hPD-1/hSTING
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Tme
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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