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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hOX40/Cd8a-IRES-Luc-2A-EGFP
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Tnf
- Description : hOX40(NM-HU-000
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hPD-1(BALB/c)
- Strain : Repository Live
- Research Application : Immunotherapy
- Nomenclature : BALB/cAnSmoc-Pd
- Description : The endogenous
- Synonyms : PD-1 Pdc1 Ly101
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hPD-1/hPD-L1
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hLAG3/hTIGIT
- Strain : Embryo cryopres
- KI/KO Gene : LAG3
- Research Application : Tumor Research
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hSTING
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tme
- Description : hPD-1(NM-HU-000
-
hPD-1/hPD-L1/hTIM3
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hTIM3(NM-HU-000
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hPD-1/hPD-L1/hIDO1
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Cancer Research
- Nomenclature : C57BL/6Smoc-Ido
- Description : hPD-1(NM-HU-000
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hPD-L1(2)/hCD28
- Strain : Embryo cryopres
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-L1(2)(NM-HU
- Synonyms : B7h1,Pdl1,Pdcd1
-
hPD-1/hTIGIT/hTIM3
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
-
hPD-L1/hCD40
- Strain : Embryo cryopres
- KI/KO Gene : CD40
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-L1(NM-HU-00
-
hPD-L1/hCD27(2)
- Strain : Repository Live
- KI/KO Gene : CD27
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-L1(NM-HU-00
-
hSIRPA(2)/hCD47/hCTLA-4
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Sir
- Description : hCTLA4(NM-HU-00
-
hSIRPA(2)/hCD47
- Strain : Repository Live
- KI/KO Gene : SIRPA
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Sir
- Description : This SIRPA and
-
h4-1BB(2)/hPD-1/hPD-L1
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tnf
- Description : h4-1BB(2)(NM-HU
-
hANGPTL3(4)
- Strain : Repository Live
- KI/KO Gene : Angptl3
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Ang
- Description : The endogenous
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