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Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hCD24(2)

    hCD24(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd24a
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd2
    • Description : The endogenous
  • hCD3E/hSDC1

    hCD3E/hSDC1

    • Strain : Repository Live
    • KI/KO Gene : CD3E
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3E(NM-HU-001
  • hCD3E/hCD20(2)

    hCD3E/hCD20(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : CD3E
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3E(NM-HU-001
  • hCD3E(2)

    hCD3E(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd3e
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : The endogenous
  • hCD3E

    hCD3E

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd3e
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : The endogenous
  • hCD3EDG/hCD28/hCD38(2)

    hCD3EDG/hCD28/hCD38(2)

    • Strain : Repository Live
    • KI/KO Gene : CD28
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3EDG/hCD28(N
  • hCD3EDG(BALB/c)

    hCD3EDG(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : CD3E
    • Research Application : Humanized Drug
    • Nomenclature : BALB/c-Cd3etm1(
    • Description : The endogenous
  • hCD73(2)

    hCD73(2)

    • Strain : Repository Live
    • KI/KO Gene : NT5E
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Nt5
    • Description : The endogenous
  • hCD40L(BALB/c)

    hCD40L(BALB/c)

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd40lg
    • Research Application : Immunotherapy
    • Nomenclature : BALB/cAnSmoc-Cd
    • Description : The endogenous
  • hCFD

    hCFD

    • Strain : Sperm cryoprese
    • KI/KO Gene : Cfd
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cfd
    • Description : The endogenous
  • hCFB

    hCFB

    • Strain : Repository Live
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cfb
    • Description : The endogenous
    • Synonyms : B, Bf, C2, Fb,
  • hCD96

    hCD96

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd96
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd9
    • Description : The endogenous
  • hCD81/hOCLN

    hCD81/hOCLN

    • Strain : Embryo cryopres
    • KI/KO Gene : CD81
    • Research Application : Hcv Infection R
    • Nomenclature : C57BL/6Smoc-Cd8
    • Description : These mice are
  • hCD80

    hCD80

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd80
    • Research Application : Cancer Research
    • Nomenclature : C57BL/6Smoc-Cd8
    • Description : The endogenous
  • hCSF1(NMG)

    hCSF1(NMG)

    • Strain : Developing
    • KI/KO Gene : Csf1
    • Research Application : Humanized Drug
    • Nomenclature : NOD-PrkdcscidIl
    • Description : The endogenous
  • hCRLF2

    hCRLF2

    • Strain : Repository Live
    • KI/KO Gene : Crlf2
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Crl
    • Description : The endogenous
  • hCTLA-4/Cd8a-IRES-Luc-2A-EGFP

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd8a
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ctl
    • Description : hCTLA4(NM-HU-00
  • Rag2-KO/hVEGFR2

    Rag2-KO/hVEGFR2

    • Strain : Embryo cryopres
    • KI/KO Gene : Rag2
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Kdr
    • Description : The Rag2 gene o
  • hIL18R1

    hIL18R1

    • Strain : Developing
    • KI/KO Gene : Il18r1
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL2

    hIL2

    • Strain : Embryo cryopres
    • KI/KO Gene : IL2
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il2
    • Description : The endogenous
  • hIL2RB

    hIL2RB

    • Strain : Embryo cryopres
    • KI/KO Gene : IL2RB
    • Research Application : Cytokine Humani
    • Nomenclature : C57BL/6Smoc-Il2
    • Description : The endogenous
  • hIL23A(BALB/c)

    hIL23A(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : Il23a
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Il
    • Description : The endogenous
  • hIL4

    hIL4

    • Strain : Embryo cryopres
    • KI/KO Gene : IL4
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il4
    • Description : The endogenous
  • hIL3/hCSF2

    hIL3/hCSF2

    • Strain : Repository Live
    • KI/KO Gene : IL3
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il3
    • Description : The endogenous
  • hKITLG(NMG)

    hKITLG(NMG)

    • Strain : Developing
    • KI/KO Gene : Kitl
    • Research Application : Immunotherapy
    • Nomenclature : NOD-PrkdcscidIl
    • Description : The endogenous