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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTNFR2/hFCGR2B
- Description : hTNFRSF1B (NM-H
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : Fcgr2b
- Synonyms : AI528646; CD32
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hSIGLEC15(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Siglec15
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hSIRPA(2)/hCD47/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hSIRPA(2)/hCD47/hCTLA-4
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CTLA4
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hSTING(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-tm
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Tmem173
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hTIM3(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ha
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Havcr2
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hTIGIT(BALB/c,2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ti
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tigit
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hTNFSF11/hSIGLEC15
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokines
- KI/KO Gene : TNFSF11
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hTNFRSF1B/hIL2RA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Embryo cryopres
- Target : Cytokines
- KI/KO Gene : TNFRSF1B
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hFCGR2B/hOX40
- Description : hFCGR2B(NM-HU-2
- Nomenclature : C57BL/6Smoc-Fcg
- Strain : Embryo cryopres
- Target : Cytokines
- KI/KO Gene : Fcgr2b
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hFCGR2B/hCD40
- Description : hFCGR2B(NM-HU-2
- Nomenclature : C57BL/6Smoc-Fcg
- Strain : Repository Live
- Target : Cytokines
- KI/KO Gene : Fcgr2b
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hFCRN(NOD-scid)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidFc
- Strain : Repository Live
- Target : Cytokines
- KI/KO Gene : Fcgrt
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hHGF(NOD-scid)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidHg
- Strain : Embryo cryopres
- Target : Cytokines
- KI/KO Gene : Hgf
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hIL11/hIL11RA
- Description : hIL11(NM-HU-204
- Nomenclature : C57BL/6Smoc-Il1
- Strain : Repository Live
- Target : Cytokines
- KI/KO Gene : Tnfrsf4
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hIL17A(BALB/C)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- Target : Cytokines
- KI/KO Gene : Il17a
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