JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Filter
Sort By

Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hGDF15

    hGDF15

    • Strain : Repository Live
    • KI/KO Gene : Faah
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Gdf
    • Description : The endogenous
  • hHER3

    hHER3

    • Strain : Repository Live
    • KI/KO Gene : Erbb3
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Erb
    • Description : The endogenous
  • hHER2

    hHER2

    • Strain : Repository Live
    • KI/KO Gene : Erbb2
    • Research Application : Tumor Research
    • Nomenclature : C57BL/6Smoc-Erb
    • Description : The endogenous
  • hHBB

    hHBB

    • Strain : Repository Live
    • KI/KO Gene : Hbb-bt
    • Research Application : Thalassemia Res
    • Nomenclature : C57BL/6Smoc-Hbb
    • Description : The endogenous
  • hICOS(2)

    hICOS(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Icos
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Ico
    • Description : The endogenous
  • hIGHG4

    hIGHG4

    • Strain : Repository Live
    • KI/KO Gene : Ighg1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Igh
    • Description : The endogenous
  • hIFNGR1/hIFNGR2

    hIFNGR1/hIFNGR2

    • Strain : Embryo cryopres
    • KI/KO Gene : IFNGR1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ifn
    • Description : hIFNGR1(NM-HU-1
  • hIL13

    hIL13

    • Strain : Embryo cryopres
    • KI/KO Gene : IL13
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL12RB2

    hIL12RB2

    • Strain : Repository Live
    • KI/KO Gene : Ccr4
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL12A/hIL12B/hIL12RB1/hIL12RB2

    • Strain : Developing
    • KI/KO Gene : Il12b
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : hIL12A(NM-HU-20
  • hIL11

    hIL11

    • Strain : Embryo cryopres
    • KI/KO Gene : Il11
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL18

    hIL18

    • Strain : Sperm cryoprese
    • KI/KO Gene : Il18
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL17A

    hIL17A

    • Strain : Embryo cryopres
    • KI/KO Gene : IL17A
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hIL1B(BALB/c)

    hIL1B(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : IL1B
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Il
    • Description : The endogenous
  • hIL1B

    hIL1B

    • Strain : Repository Live
    • KI/KO Gene : Il1b
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il1
    • Description : The endogenous
  • hTHPO

    hTHPO

    • Strain : Embryo cryopres
    • KI/KO Gene : Thpo
    • Research Application : Cytokine Humani
    • Nomenclature : C57BL/6Smoc-Thp
    • Description : The endogenous
  • hTLR9/hOX40

    hTLR9/hOX40

    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tlr
    • Description : This TLR9 and O
  • hTLR9

    hTLR9

    • Strain : Embryo cryopres
    • KI/KO Gene : Tlr9
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tlr
    • Description : This TLR9 human
  • hTLR8/Lyz2-DTREGFP

    hTLR8/Lyz2-DTREGFP

    • Strain : Embryo cryopres
    • KI/KO Gene : TLR8
    • Research Application : Tumor Research
    • Nomenclature : C57BL/6Smoc-Lyz
    • Description : NM-KI-190041 wa
  • hTLR4

    hTLR4

    • Strain : Embryo cryopres
    • KI/KO Gene : Tlr4
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tlr
    • Description : The endogenous
  • hTIGIT/hTNFR2

    hTIGIT/hTNFR2

    • Strain : Repository Live
    • KI/KO Gene : CTLA4
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tig
    • Description : hTIGIT(3)(NM-HU
  • hTNFR2/hPD-1

    hTNFR2/hPD-1

    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : hTNFRSF1B(NM-HU
  • hTNFR2

    hTNFR2

    • Strain : Repository Live
    • KI/KO Gene : TNFRSF1B
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : The endogenous
  • hTSLP/hIL17RA

    hTSLP/hIL17RA

    • Strain : Embryo cryopres
    • KI/KO Gene : TSLP
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tsl
    • Description : hTSLP(NM-HU-200
  • hTSLP

    hTSLP

    • Strain : Embryo cryopres
    • KI/KO Gene : TSLP
    • Research Application : Asthma Research
    • Nomenclature : C57BL/6Smoc-Tsl
    • Description : The endogenous