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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hSIGLEC15(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Siglec15
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hSIRPA(2)/hCD47/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
-
hSIRPA(2)/hCD47/hCTLA-4
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CTLA4
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hSTING(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-tm
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Tmem173
-
hTIM3(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ha
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Havcr2
-
hTIGIT(BALB/c,2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ti
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tigit
-
hTNFSF11/hSIGLEC15
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokines
- KI/KO Gene : TNFSF11
-
hTNFRSF1B/hIL2RA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Embryo cryopres
- Target : Cytokines
- KI/KO Gene : TNFRSF1B
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