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Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • pAtp4b-hCLDN18.2-Tg

    pAtp4b-hCLDN18.2-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hSORT1

    hSORT1

    • Nomenclature : C57BL/6JSmoc-So
    • KI/KO Gene : Sort1
    • Strain : Embryo cryopres
    • Target : Tumor Targets
    • Description : Model Descripti
  • pCdh16-hENPP3-Tg

    pCdh16-hENPP3-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hCLDN18.2-Tg

    hCLDN18.2-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hCD19-Tg

    hCD19-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hENG

    hENG

    • Nomenclature : C57BL/6JSmoc-En
    • KI/KO Gene : Eng
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hCEACAM6-Tg

    hCEACAM6-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • KI/KO Gene : Tgtn(hCEACAM6)1
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hSEMA4D

    hSEMA4D

    • Nomenclature : C57BL/6JSmoc-Se
    • KI/KO Gene : Sema4d
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Tumor Targets
  • hTPBG

    hTPBG

    • Nomenclature : C57BL/6JSmoc-Tp
    • KI/KO Gene : Tpbg
    • Strain : Repository Live
    • Target : Tumor Targets
    • Description : Model Descripti
  • hTP53(2)

    hTP53(2)

    • Nomenclature : C57BL/6JSmoc-Tr
    • KI/KO Gene : Trp53
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hLILRB1-hLILRB2-Tg

    hLILRB1-hLILRB2-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • Description : Model Descripti
  • hSERPINA1

    hSERPINA1

    • Nomenclature : C57BL/6JSmoc-Se
    • KI/KO Gene : Serpina1e
    • Strain : Repository Live
    • Target : Tumor Targets
    • Description : Model Descripti