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Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hSERPINH1

    hSERPINH1

    • Nomenclature : C57BL/6JSmoc-Se
    • KI/KO Gene : Serpinh1
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hVEGFA(2)

    hVEGFA(2)

    • Nomenclature : C57BL/6JSmoc-Ve
    • KI/KO Gene : Vegfa
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hAPP

    hAPP

    • Nomenclature : C57BL/6JSmoc-Ap
    • KI/KO Gene : App
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • hBACE1

    hBACE1

    • Nomenclature : C57BL/6JSmoc-Ba
    • KI/KO Gene : Bace1
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • hSOST(2)

    hSOST(2)

    • Nomenclature : C57BL/6JSmoc-So
    • KI/KO Gene : Sost
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hSERPINC1

    hSERPINC1

    • Nomenclature : C57BL/6JSmoc-Se
    • KI/KO Gene : Serpinc1
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hSOST

    hSOST

    • Nomenclature : C57BL/6JSmoc-So
    • KI/KO Gene : Sost
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hSNCA

    hSNCA

    • Nomenclature : C57BL/6JSmoc-Sn
    • KI/KO Gene : Snca
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • hVEGFA

    hVEGFA

    • Nomenclature : C57BL/6JSmoc-Ve
    • KI/KO Gene : Vegfa
    • Research Application : Immunotherapy
    • Strain : Repository Live
    • Target : Other Targets
  • hMC5R

    hMC5R

    • Nomenclature : C57BL/6JSmoc-Mc
    • KI/KO Gene : Mc5r
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hSPP1

    hSPP1

    • Nomenclature : C57BL/6JSmoc-Sp
    • KI/KO Gene : Spp1
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hSPN

    hSPN

    • Nomenclature : C57BL/6JSmoc-Sp
    • KI/KO Gene : Spn
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • R26-CAG-LSL-hPLA2R1-IRES-EGFP

    • Nomenclature : C57BL/6JSmoc-Gt
    • KI/KO Gene : Pla2r1
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • hADAM17

    hADAM17

    • Nomenclature : C57BL/6JSmoc-Ad
    • KI/KO Gene : Adam17
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • hSOD1

    hSOD1

    • Nomenclature : C57BL/6JSmoc-So
    • KI/KO Gene : Sod1
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hTEK

    hTEK

    • Nomenclature : C57BL/6JSmoc-Te
    • KI/KO Gene : Tek
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • Itgam-IRES-hCD89/hIGHA1

    Itgam-IRES-hCD89/hIGHA1

    • Nomenclature : C57BL/6JSmoc-It
    • KI/KO Gene : Itgam
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti