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Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • pAlb-hLPA-Tg

    pAlb-hLPA-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : LPA
  • pAlb-hAPOB-Tg

    pAlb-hAPOB-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : APOB
  • hAPOE2

    hAPOE2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Embryo cryopres
    • Target : Metabolic Targe
    • KI/KO Gene : Apoe
  • hAPOE3

    hAPOE3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : Apoe
  • hTTR

    hTTR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tt
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : Ttr
  • hANGPTL4

    hANGPTL4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-An
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : Angptl4
  • hAPOE4

    hAPOE4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : Apoe