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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
41 Result Found
-
hSIRPA/hCD47(BALB/c)
- Nomenclature : BALB/cAnSmoc-Si
- KI/KO Gene : SIRPA
- Research Application : Tumor research
- Strain : Repository Live
- Target : Immune Checkpoi
-
hSIRPA(2)/hCD47/hPD-1/hPD-L1
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Strain : Repository Live
- Target : Immune Checkpoi
-
hTIGIT/hPVR
- Nomenclature : C57BL/6JSmoc-Ti
- KI/KO Gene : TIGIT
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Immune Checkpoi
-
hNCR3LG1-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- KI/KO Gene : Tgtn( hNCR3LG1)
- Strain : Developing
- Target : Immune Checkpoi
- Description : Model Descripti
-
hCD3EDG/hPSMA
- Nomenclature : C57BL/6JSmoc-Cd
- KI/KO Gene : CD3E
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- Description : Model Descripti
-
hSIRPA(2)/hCD47/hPD-L1
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : Cd274
- Research Application : Immunotherapy
- Strain : Repository Live
- Target : Immune Checkpoi
-
hTLR8/Lyz2-DTREGFP
- Nomenclature : C57BL/6JSmoc-Ly
- KI/KO Gene : TLR8
- Research Application : Tumor research
- Strain : Embryo cryopres
- Target : Immune Checkpoi
-
hSIGLEC15(BALB/c)
- Nomenclature : BALB/cAnSmoc-Si
- KI/KO Gene : Siglec15
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Immune Checkpoi
-
hSIRPA(2)/hCD47/hPD-1
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : Pdcd1
- Research Application : Immune-related
- Strain : Embryo cryopres
- Target : Immune Checkpoi
-
hSIRPA(2)/hCD47/hCTLA-4
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : CTLA4
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Target : Immune Checkpoi
-
hSTING(BALB/c)
- Nomenclature : BALB/cAnSmoc-tm
- KI/KO Gene : Tmem173
- Research Application : Immunotherapy
- Strain : Repository Live
- Target : Immune Checkpoi
-
hTIGIT(BALB/c,2)
- Nomenclature : BALB/cAnSmoc-Ti
- KI/KO Gene : Tigit
- Strain : Developing
- Target : Immune Checkpoi
- Description : Model Descripti
-
Rag2/IL2rg-KO/hCD40
- Nomenclature : C57BL/6JSmoc-Cd
- KI/KO Gene : CD40
- Research Application : Immunotherapy
- Strain : Developing
- Target : Immune Checkpoi
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