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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
41 Result Found
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hSIRPA/hCD47(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : SIRPA
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hSIRPA(2)/hCD47/hPD-1/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
-
hTIGIT/hPVR
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ti
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : TIGIT
-
hNCR3LG1-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tgtn( hNCR3LG1)
-
hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
-
hSIRPA(2)/hCD47
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : SIRPA
-
hTLR8/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tl
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
-
Rag2/IL2rg-KO/hSIRPA(2)/hCD47
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : IL2RG
-
hCD3EDG/hB7H3
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD276
-
hCD3EDG/hPSMA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
-
hSIRPA(2)/hCD47/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
-
hTLR8/Lyz2-DTREGFP
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ly
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : TLR8
-
hSIGLEC15(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Siglec15
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