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Humanized Knockins

Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

  • hTNFRSF8

    hTNFRSF8

    • Nomenclature : C57BL/6JSmoc-Tn
    • KI/KO Gene : Tnfrsf8
    • Strain : Developing
    • Target : Cytokine Recept
    • Description : Model Descripti
  • hLILRB1-hLILRB4-Tg

    hLILRB1-hLILRB4-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • KI/KO Gene : LILRB4
    • Strain : Repository Live
    • Target : Cytokine Recept
    • Description : Model Descripti
  • hTNFRSF13C

    hTNFRSF13C

    • Nomenclature : C57BL/6JSmoc-Tn
    • KI/KO Gene : Tnfrsf13c
    • Strain : Developing
    • Target : Cytokine Recept
    • Description : Model Descripti
  • hTNFRSF1A

    hTNFRSF1A

    • Nomenclature : C57BL/6JSmoc-Tn
    • KI/KO Gene : Tnfrsf1a
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • Description : Model Descripti
  • hTNFRSF10B

    hTNFRSF10B

    • Nomenclature : C57BL/6JSmoc-Tn
    • KI/KO Gene : Tnfrsf10b
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
  • hCXCR5

    hCXCR5

    • Nomenclature : C57BL/6JSmoc-Cx
    • KI/KO Gene : Cxcr5
    • Strain : Developing
    • Target : Cytokine Recept
    • Description : Model Descripti