Loading ....
BHE12104863
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
Continuing the saving: $50 Off All ELISA Kits Offer Extended!
Contact us to order
Tel
+1 866.986.9598
Bioassay Technology Laboratory
view supplier detailsCredit card payments now incur a 3% fee.
