In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity(By similarity). Might affect PCNA interaction with some CDK(cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Categories
Primary Antibodies
Clonality
polyclonal
Description
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Host
Rabbit
Immunogen
growth arrest and DNA-damage-inducible, alpha
Isotype
IgG
Molecular Weight
18 kDa or 25 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DDIT1, GADD45
Uniprot
P24522
Gene Id
23645
Research Area
Epigenetics
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)