4AE56 reacts with L-selectin, an 80 kDa leukocyte-endothelial cell adhesion molecule 1 (LECAM-1). CD62L is expressed on most peripheral blood B cells, T cells, some NK cells, monocytes and granulocytes. CD62L mediates lymphocyte homing to high endothelial venules of peripheral lymphoid tissue and leukocyte rolling on activated endothelium at inflammatory sites. 1. Bevilacqua, M et al ( 1991) : Cell 67:233.2. Polley, MJ et al ( 1991) , Proc. Natl. Acad. Sci. USA 88:6224.3. Smith, CW et al ( 1991) J Clin. Invest . 87:609.4. Picker, LJ et al ( 1991) Cell 66:921.
Host
Mouse
Isotype
IgG1
Raised In
Mouse
Reactivity
Human
Regulatory
RUO
Relevance
4AE56 reacts with L-selectin, an 80 kDa leukocyte-endothelial cell adhesion molecule 1 (LECAM-1). CD62L is expressed on most peripheral blood B cells, T cells, some NK cells, monocytes and granulocytes. CD62L mediates lymphocyte homing to high endothelial venules of peripheral lymphoid tissue and leukocyte rolling on activated endothelium at inflammatory sites.
1. Bevilacqua, M et al ( 1991) : Cell 67:233.
2. Polley, MJ et al ( 1991) , Proc. Natl. Acad. Sci. USA 88:6224.
3. Smith, CW et al ( 1991) J Clin. Invest . 87:609.