COCL reacts with CD10, 100 kDa common acute lymphoblastic leukemia antigen (CALLA), which is expressed on lymphoid precursors, germinal center B cells, and peripheral blood granulocytes. CD10 is a regulator of B cell growth and proliferation. CD10 antibody is used in conjunction with other reagents in the phenotyping of leukemia.*CD10 is a phenotyping marker of leukemic cells that may have prognostic significance in leukemia clinical application. 1. McMichael,AJ. Ceds.(1987) Leucocyte Typing III: White Cell Differentiation Antigen, Oxford University Press, New York.2. Letarte, M. et al., (1988) J. Exp. Med. 168:1247.3. Le Bien TW and McCormack, RT. (1989) Blood 73:625-635.4. Consolini R et al. (1998) Hematologica 83:967-973
Host
Mouse
Isotype
IgG1
Raised In
Mouse
Reactivity
Human
Regulatory
RUO
Relevance
COCL reacts with CD10, 100 kDa common acute lymphoblastic leukemia antigen (CALLA), which is expressed on lymphoid precursors, germinal center B cells, and peripheral blood granulocytes. CD10 is a regulator of B cell growth and proliferation. CD10 antibody is used in conjunction with other reagents in the phenotyping of leukemia.
*CD10 is a phenotyping marker of leukemic cells that may have prognostic significance in leukemia clinical application.
1. McMichael,AJ. Ceds.(1987) Leucocyte Typing III: White Cell Differentiation Antigen, Oxford University Press, New York.
2. Letarte, M. et al., (1988) J. Exp. Med. 168:1247.
3. Le Bien TW and McCormack, RT. (1989) Blood 73:625-635.
4. Consolini R et al. (1998) Hematologica 83:967-973