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Home / Primary Antibodies / Monoclonal Antibodies

ITGAM Monoclonal Antibody,FITC Conjugated

SKU : BHA10561220

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA270358
Categories	Primary Antibodies
Clonality	monoclonal
Description	4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.* CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.This clone is cross reactive with non-human primate. 1. Ling NR et al., eds. (1987) Leucocyte Typing III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-3342. Petty HR nd Todd RF. (1996) Immunol. Today 17:2093. Springer TA (1994) Cell 76:3014. Stewart M et al (1995) Curr Opin Cell Biol 7:690
Host	Mouse
Isotype	IgG1
Raised In	Mouse
Reactivity	Human
Regulatory	RUO
Relevance	4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis. * CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections. This clone is cross reactive with non-human primate. 1. Ling NR et al., eds. (1987) Leucocyte Typing III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-334 2. Petty HR nd Todd RF. (1996) Immunol. Today 17:209 3. Springer TA (1994) Cell 76:301 4. Stewart M et al (1995) Curr Opin Cell Biol 7:690
Species	Homo Sapiens (Human)

Buffer	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Format	liquid
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF, FC

Description

ELISA ; IF ; FC, FACS ; ELISA ; IF

Dilution

IF	1:100-1:200

Tested Application

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561220	CSB-MA270358	100ul	$258		Add to Cart

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