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Home / Primary Antibodies / Flow Cytometry (FACS)

ITGAL Monoclonal Antibody,FITC Conjugated

SKU : BHA10561218

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA120024
Categories	Primary Antibodies
Clonality	monoclonal
Description	4A122 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate. 1. Schlossman. S et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York.2. Lub M et al. (1995) Immunol. Today 16:479.3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7:99.
Host	Mouse
Isotype	IgG1
Raised In	Mouse
Reactivity	Human
Regulatory	RUO
Relevance	4A122 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium. *CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate. 1. Schlossman. S et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. 2. Lub M et al. (1995) Immunol. Today 16:479. 3. Sanchez-Mateos P et al. (1996) Cancer Biol. 7:99.
Species	Homo Sapiens (Human)

Clone No	4A122

Buffer	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Format	liquid
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF, FC

Description

ELISA ; IF ; FC, FACS ; ELISA ; IF

Dilution

IF	1:100-1:200

Tested Application

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561218	CSB-MA120024	100ul	$258		Add to Cart

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